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Semaglutide reaching an average weight loss of [about] 15% was game-changing in 2021, he said, changing clinical benefit from improvement to remission of other conditions like hypertension, hyperlipidemia and diabetes. Weight loss of 25%, Moreno and Grunvald noted, would reach results obtained by bariatric surgery

These hormones are pivotal regulators of hunger and food consumption

However, there have been no human trials, so the safety risks and effectiveness for patients are unknown

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