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(2021) have revealed the strong neuroprotection and antioxidant ability of water kefir against hydrogen peroxide induced oxidative stress in neuroblastoma cells (SH-SY5Y) which was often used as a model to study neurodegenerative disease, and the effects were mediated through the improvement of superoxide dismutase, catalase and apoptotic genes regulation in preventing oxidative stress

Billings JL, Hare DJ, Nurjono M, Volitakis I, Cherny RA, Bush AI et al

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This robust defense systemworks well for us when were healthy, but in disease states, our defense against oxidants is weakened and the oxidant load increases to deleterious levels