3 In B12 deficiency, methylmalonic acid (MMA) can accumulate, and it is thought that elevated MMA, alongside elevated homocysteine, contributes to damage of the myelin sheath (which protects nerve cells and speeds up nerve transmission), which can cause irreversible neurological problems
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Surprisingly, introduction of the C347K/R mutation in the receptor rescued the activity of the seven residue N-terminal truncation in the EX4 peptide (Figure 5a and b group I, expression level shown in Supplementary Figure S1B)
Clarithromycin for early anti-inflammatory responses in community-acquired pneumonia in Greece (ACCESS): a randomised, double-blind, placebo-controlled trial