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Experientia (1993) 49(12):10847.10.1007/BF01929917 40 JoshiPCGrayTAKeaneTC
Compared to native glucagon and GLP-1, retatrutide shows lower potency at GLP-1 and glucagon receptors but higher potency at the GIP receptor
Overall, both classes are indifferently recommended by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) as first-line therapy in patients with T2DM and established ASCVD or multiple ASCVD risk factors to reduce the risk of major adverse cardiovascular events (MACE), such as myocardial infarction, stroke, and cardiovascular death [6, 7]
intragastric: An adjective referring to something that is in or takes place within the stomach
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