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In the cytoplasm, Keap1 homodimer forms ubiquitin E3 ligase complex with cullin 3 (Cul3), which polyubiquitinates Nrf2 protein leading to its continuous proteasomal degradation ( Figure 3, right)

Mechanistic aspects of the tyrosinase oxidation of hydroquinone

At Allegro Pediatrics, our goal is to provide accurate, evidence-based information to help patient families make informed decisions about your childs care

11 , S23S32 (1995)