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Cannabis, in particular, is one of the oldest recreational substances with a long history of use, while MDMA has been extensively studied for its recreational effects since its emergence several decades ago

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Supramolecular regulation of bioorthogonal catalysis in cells using nanoparticle-embedded transition metal catalysts

The reconstitution process must achieve two objectives: Complete solubilisation without mechanical stress that could disrupt peptide bonds Maintenance of pH neutrality to prevent hydrolysis of the C-terminal valine residue The choice of reconstitution vehicle directly impacts these factors