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g , Mechanically induced firing frequencies of fibers from control and arthritis mice, thick lines represent mean number of action potentials in 1 second bins, shadowed regions are the s.e.m

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Interestingly, our findings also revealed that treatment with N-3 PUFAs alone increased VDR expression three-fold, This finding highlights the potential of N-3 PUFAs to enhance VDR expression independently, which could represent a novel way of neuroprotection, suggesting an additional mechanism for the synergistic neuroprotective effect observed in rats receiving the combined treatment, that was primarily associated with reduced neuronal apoptosis, tauopathy, and proinflammatory status in the brain