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Similarly, a meta-analysis of nine observational studies in older adults found low serum vitamin B 12 concentration to be associated with increased risk for depression, with significant association only in women (100)

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Timing and administration details The timing matters more than most people realize

Do not administer this drug to the following patients: 1) Patients with hypersensitivity to the components of this drug 2) Patients with hypercalcemia, hypercalciuria 3) Patients with calcium oxalate stones 4) Patients with renal impair 5) Patients who are immobilized in a hospital bed 6) Sarcoidosis 7) Patients with pseudoparathyroidism 3