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Endocrine 73:815 Burch HB, Perros P, Bednarczuk T, Cooper DS, Dolman PJ, Leung AM, Mombaerts I, Salvi M, Stan MN (2022) "Management of thyroid eye disease: a consensus statement by the American Thyroid Association and the European Thyroid Association." European thyroid journal 11(6)

Due to the rising demand for weight loss drugs and the resulting drug shortages, some specialized compounding pharmacies were allowed to make compounded semaglutide injections

Following large-scale liver injury, Notch signaling upregulates the expression of the insulin-like growth factor 1 receptor (IGF1R) in BECs and sensitizes BECs to IGF1, which promotes IGF1-induced BEC proliferation

Serious Adverse Events: Pancreatitis, Thyroid, and Kidney Function Rare but serious side effects include acute pancreatitis (0.1-0.3% in trials), gallbladder issues, and thyroid C-cell tumors in animal models