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10.1136/gutjnl-2019-319990 66 MurphyN.JenabM.GunterM

Afshin A, et al

Most people experience mild to moderate intensity headaches rather than severe migraines, though pre-existing migraine conditions can increase severity

In a meta-analysis 6 of eight trials with 60080 patients (ELIXA, LEADER, SUSTAIN-6, EXSCEL, Harmony Outcomes, REWIND, PIONEER 6, and AMPLITUDE-O) , treatment with a GLP-1 receptor agonist led to a 14% relative risk reduction in three-point MACE (HR 086 [95% CI 080093]