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Korean J Inter Med
Relative expression (RE) Western blot analysis of Glutathione Peroxidase 3 / GPx-3 on different lysates with Rabbit anti-Glutathione Peroxidase 3 / GPx-3 antibody (HA751612) at 1/5,000 dilution
In vitro experiments with Vero hTMPRSS2 cells, Calu-3 and primary human airway epithelial cell lines and using gene silencing of Keap1 and Nrf2 agonists 4-octyl-itaconate (4-OI) and dimethyl fumarate (DMF), it was shown that the Nrf2 pathway has a critical role in inhibiting SARS-CoV-2 replication, in addition to limiting the host inflammatory response
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