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The catch is that the rigorous trial evidence is mixed

Furthermore, contrary to what the aforementioned article would have readers believe, lipedema is a slowly progressive fat disorder that is only noticeable after puberty, and only slowly becomes more noticeable as the women grow older

Recently it was identified that the SR sCD163 (SR-I1) was elevated in patients suffering from LN, and it was suggested to be used as a prognostic biomarker (59)

It is also possible that factors such as treatment cost, insurance coverage or how advanced a persons diabetes was played a role in which medication they were prescribed, which could create differences between the two groups that were difficult to fully measure