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To examine the similarity of peptides predicted by different models within each potency profile, we used PCA, considering the 500 one-hot-encoded sequences generated across all five compared models, the wild-type peptideshGCG and hGLP-1and their single-step mutants (551 hGCG and 570 hGLP-1), such that the projection was computed for an array [1,621 21 L ]

At the end of the incubation periods, a CFU count (T72) was performed

Both MT1 and MT2 are contraindicated in subjects who are pregnant, breastfeeding, under 18 years of age, or who have a prior history of skin-related malignancies