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Description

This review summarizes the most recent studies that reframe our understanding of the physiology of GLP-1 in health and disease

Although much of this evidence derives from animal models, making direct extrapolation to humans complex, significant functional commonalities exist between the murine and human BBB, including glucose transport, the presence of circumventricular organs (CVOs), and saturable transport systems [33]

Along with controlling glycemia and reducing insulin resistance, GLP-1RAs also reduce diabetic neuropathic pain by suppressing neuroinflammation in the spinal cord

ISSN 2836-7677