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The cytoprotective role of Sp was further evaluated through determination of mitochondrial function and amount of intracellular lipid peroxides quantified by measuring the levels of their decomposed carbonyl product malondialdehyde

After three cycles of ifosfamide (1,800 mg/m2/day for 5 days) as continuous infusion with mesna, and doxorubicin (37.5 mg/m2/day intravenously for 2 days), a repeat PET/CT scan revealed further tumor progression

Trout L, Corboz MR, Ballard ST

A phase Ib trial with a 4-week subcutaneous administration of either 10 mg or 15 mg tirzepatide once weekly in subjects with T2D led to a significant reduction in fasting plasma glucose concentrations (LSM difference [95% CI]: 49.12 mg/dl [78.14, 20.12] and 43.15 mg/dl [73.06, 13.21], respectively) and to reductions in body weight (LSM difference [95% CI]: 2.62 kg [3.79, 1.45] and 2.07 kg [3.25, 0.88], respectively