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Genetic Ablation of the Cystine Transporter xCT in PDAC Cells Inhibits mTORC1, Growth, Survival, and Tumor Formation via Nutrient and Oxidative Stresses

AtMORF2 acts as chaperone that directly promotes the accumulation of several tetrapyrrole biosynthetic enzymes and participates in tetrapyrrole biosynthesis (TBS) 46,63,64

This is especially true for glutathione, which has poor oral bioavailability

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