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Hypercholesterolemia causes psychomotor abnormalities in mice and alterations in cortico-striatal biogenic amine neurotransmitters: relevance to Parkinson's disease

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Much of the research over the last couple of decades has focused on thrombosis and reducing the risk of excessive blood clotting, as this is substantially associated with vascular stiffness, reduced blood flow, and an increased risk of embolism, cardiovascular disease, and heart failure