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Theyre also planning studies to investigate how tirzepatide might help with chronic kidney disease and with understanding how it impacts health in people with obesity

Environmental factors, including diet, physical activity levels, endocrine disorders, dysbiosis of the gastrointestinal microbiota, and genetic predisposition, can significantly influence disease development and outcomes [21]

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found that in the early compensatory stage, gut -diversity begins to decline along with reductions in SCFA-synthesizing species, despite no significant changes in overall species abundance (Spehlmann et al., 2022)