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Notable recent developments include the first preclinical study demonstrating NNMT inhibition improves cardiac function and reduces fibrosis in a heart failure model (Li et al., 2025), a comprehensive review of NNMT as a therapeutic target for neurodegenerative disorders (Liu et al., 2025), and emerging evidence that NNMT inhibition counteracts tubular senescence and fibrosis in chronic kidney disease
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USA 107 , 2121121216 (2010)
In Europe alone, almost one million people suffer from the top 12 most common groups of rare diseases, for which plasma-derived therapies offer potentially life-changing treatment
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