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The methods for Supplementary Figures can be found in the Supplementary Information

So it's not only a simple solution to obesity, but it also is becoming a kind of drug or a classification of drug that meets a number of chronic health conditions, and that kind of classification of drug is requiring a new level of regulation and also pricing conversations across the insurance and the healthcare industries as well as in the policy sectors

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So now we no longer have that stimulating effect of blood sugar coming from the liver, so we shutting that off