diseases associated with low glutathione What are the Symptoms of Deficiency? – Core Med Science PDF) Evidence of oxidative damage

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Glutathiones reduced form (GSH): Carries an extra electron (hydrogen) Donates hydrogen (electron) to inflammation-causing free radicals to neutralize their effect Glutathione peroxidase enzyme Requires selenium Converts two hydrogen peroxides into two water molecules Glutathiones oxidized form (GSSG): State of glutathione after losing its electron Forms a disulfide bridge between two glutathione molecules Glutathione reductase enzyme Glutathione can be recycled back to its reduced form using NADPH (reducing agent, electron donor)

10.3390/antiox12030658 44 Colon HidalgoD.ElajailiH.SulimanH.GeorgeM

This relaxation can lead to stomach acid flowing back into the esophagus, causing symptoms of GERD