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Redox regulation of PTPN22 affects the severity of T-cell-dependent autoimmune inflammation

Some signs of B12 deficiency in chickens include: Leg weakness Nervous system impairment Perosis Poor feathering Reduced hatch rates (from deficient parents embryos frequently die at around 17 days old) Most commercial chicken feed contains B vitamins, so B12 deficiency is less common

This review highlights the integrated roles of Mn transporters, including ZIP8, ZIP14, and ZNT10, in maintaining systemic and cellular Mn homeostasis and how their dysfunction leads to tissue-specific vulnerability

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