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Shatsky[23], who examined evidence derived from the use of oral and intramuscular administration, indicated that high dose oral administration appeared to be safe, effective and cost-effective, although long term clinical trials were required to confirm this

2.8 In vivo evaluation of MitoQ and DPI: tolerability and limited efficacy in NB mouse models Finally, to evaluate the efficacy of MitoQ and DPI in vivo , both drugs were administered individually and in combination to Th- MYCN transgenic NB mice

1 mg is equal to 1000 mcg

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