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doi:10.1002/nbm.4227 112. Shimizu, T., Iwanaga, M., Yasunaga, A., Urata, Y., Goto, S., Shibata, S., & Kondo, T

FIGURE 3 GO and KEGG analyses of the 59 aforementioned candidate targets indicated that the biological process (BP) terms of the target genes were mainly involved in the positive regulation of cell proliferation (GO:0008284), protein phosphorylation (GO:0006468), positive regulation of cell migration (GO:0030335), and negative regulation of apoptosis (GO:0043066)

In both cases, regular, consistent use within an appropriate routine is the practical takeaway, not a precise clock time

The lack of evidence may also be an issue of strengthening protocol