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Description

AOD-9604 does not cause water loss or glycogen depletion the way GLP-1 agonists do, so there is no early "whoosh" effect

These combined mechanisms contribute to an extended elimination half-life of approximately 5.6 to 7.5 days [28]

This area lacks large clinical trials specific to retatrutide combinations, but the theoretical rationale is sound: using one compound for fat loss and another for muscle preservation addresses both sides of the body composition equation simultaneously

However, their dosing protocols differ considerably