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Pharmacological interventions that restore 5-HT signaling, such as selective serotonin reuptake inhibitors (SSRIs), ameliorate depressive-like behaviors in ethanol-exposed mice, but only in subsets of animals, echoing the variable efficacy of SSRIs in human AUD populations (Khan et al

J Nanoparticle Res 15(7):1770

Gastrointestinal mucosa: Animal models indicate cytoprotective and pro-healing effects on gastric and intestinal tissues, including angiogenesis-linked repair

This regulatory positioning aligns it with research into adaptive resilience mechanisms within the central nervous system