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The approval of the clinical trial of this product is another important achievement of our group's layout in the field of cell therapy, laying a good foundation for the development of cell therapy products including in vivo generated CAR-T

PPP did not compete with ATP but interfered with phosphorylation in the activation loop of the kinase domain, in which it specifically blocked phosphorylation of the tyrosine (Y) 1136 residue, while sparing the two others (Y1131 and Y1135)

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