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The safest approach is to discard the vial and start over with a fresh one, using a new, sharp needle inserted straight through the stopper center

Cancer Cell 19 , 387400 (2011)

Another BBB-crossing molecule with HGF-like activity, BB3, was employed in pre-clinical models of stroke, showing good functional improvements (Prat et al., 1998

in the New England Journal of Medicine in 2023