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IL33-STAT3-MMP2/9 is reported to play an important role in macrophage polarization from anti-inflammatory phenotype (M2) to proinflammatory phenotype (M1), thus inducing lipopolysaccharide (LPS)-induced ALI and pulmonary inflammation
Sci Transl Med 7:273ra15 Fuxe K, Agnati LF, Jacobsen K, Hillion J, Canals M, Torvinen M, Tinner-Staines B, Staines W, Rosin D, Terasmaa A, Popoli P, Leo G, Vergoni V, Lluis C, Ciruela F, Franco R, Ferr S (2003) Receptor heteromerization in adenosine A2A receptor signaling: relevance for striatal function and Parkinsons disease
These results are shown graphically in Fig
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