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Typical trial exclusion criteria for retatrutide studies, consistent with those applied to similar investigational and licensed medicines in this class, have included: pregnancy or breastfeeding (with active contraception requirements during participation)

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By elucidating the critical roles of ROS homeostasis in cellular physiology and disease treatment, this review aims to advance the discovery of potential biomarkers as well as the development of novel therapeutic approaches based on ROS homeostasis