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When to discard a vial Discard immediately if: The solution turns cloudy or develops visible particles You notice any color change from the original appearance The vial has been at room temperature for an extended period (check the pharmacy guidelines for your specific formulation) More than 28-30 days have passed since first puncture You suspect any contamination Tirzepatide is a large peptide molecule that degrades with heat, light, and bacterial contamination

Data Sources and Eligibility Criteria Eligible studies included RCTs, observational cohort studies, meta-analyses, and large pharmacovigilance analyses published in English

This translates to a difference of 6.5% in mean weight decrease, compared with 20.2% for those receiving semaglutide, a 14% weight decrease

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