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Although the actual mechanisms of MTX-induced liver and kidney damage are unknown, one of the hypotheses is the breakdown in cellular antioxidant defences, which increases the production of reactive oxygen species and nitrogen species, inhibits cytosolic NADP-dependent dehydrogenase and NADP malic enzyme, lowers glutathione (GSH), superoxide dismutase (SOD) and catalase levels and reduces the effectiveness of the antioxidant defence system protecting the cell against reactive oxygen species (Reference Savran, Cicek and Doguc7)

The lightweight formula absorbs quickly, delivering essential nutrients deep into the skin without leaving any greasy residue

Antioxidant defence Like vitamin E, vitamin C is also a powerful antioxidant that protects the lips from free radical damage

It increases liver and kidney-based production of a nutrient that can burn fat, improve muscle performance and reduce fatigue