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For example, production of the neurotransmitter, 5-HT/serotonin, was reportedly upregulated in the presence of spore-forming Clostridia species , while germ-free mice displayed lower 5-HT/serotonin levels in their colon and blood as well as reduced intestinal motility (Kashyap et al

STEP 1 enrolled over 1,900 adults without diabetes and showed an average weight loss of 14.9 percent of body weight over 68 weeks

In fact, some studies suggest drinking too many of these cocktails could lead to riskier behavior, heart palpitations, and insomnia

Additional information Peer review information Nature Metabolism thanks Dominique Langin and the other, anonymous reviewers for their contribution to the peer review of this work