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Neuropsychiatric monitoring is particularly important: Mood changes : Report any worsening depression, increased anxiety, or suicidal thoughts immediately Sleep disturbances : Both medications can affect sleep patterns Fatigue or dizziness : May impair ability to drive or operate machinery Serotonin syndrome : A rare but serious condition associated with SSRIs, especially when combined with other serotonergic medications (not related to semaglutide) Metabolic and other considerations : Blood glucose effects : Wegovy can affect blood glucose levels

Das SS, Hayashi H, Sato T, Yamada R, Hiratsuka M, Hirasawa N

Patients should avoid lying down immediately after eating and finish meals at least 2-3 hours before bedtime to minimize reflux symptoms

Eating smaller, more frequent meals, avoiding high-fat foods, staying hydrated, and having ginger tea available all help manage these effects