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[1] Without early administration of the antidote, fulminant liver failure follows, often in combination with kidney failure, and death generally occurs within several days

Of note, modelling work suggests that combined GLP-1 and amylin receptor agonism may attenuate the post-treatment weight regain sometimes observed after semaglutide withdrawal, an effect already hinted at in extension cohorts

Further research is needed to define subgroups of children with ASD in which these treatments may be most effective as well as confirm their efficacy in DBPC, large-scale multicenter studies

Hydrophobic nanoparticles tend to be more readily taken up by antigen-presenting cells (APCs), eliciting stronger immune activation [44]