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Diabetic ketoacidosis (DKA) While considered lower-risk than with SGLT2 inhibitors, DKA can still occur in people with type 1 diabetes taking tirzepatide, particularly if the insulin dose is reduced too aggressively or if the person becomes unwell (e.g

Excess body weight elevates estrogen relative to testosterone, raises core body temperature in the scrotum (which impairs sperm production), and increases oxidative stressall mechanisms that semaglutide-driven weight loss can reverse

Chronic sleep deprivation can have serious consequences for physical and psychological wellbeing, and persistent insomnia may necessitate referral for cognitive behavioural therapy for insomnia (CBT-I), which is recommended by NICE as the first-line treatment for persistent sleep problems

Adrenal Fatigue: The 21st Century Stress Syndrome