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Prolongation of the fasting period in this situation is not recommended, given the lack of safety evidence
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What UK clinical guidance says The Wegovy Summary of Product Characteristics (the formal MHRA-approved prescribing document) section 4.6 states that semaglutide shouldnt be used during pregnancy, and that if a patient wishes to become pregnant, semaglutide should be stopped at least two months before a planned pregnancy due to the long half-life
Both carry a boxed warning about thyroid C-cell tumours based on rodent studies
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