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In contrast, in normal non-cancer rectal tissue, metformin significantly altered the secretion of only three IL-17 related cytokines, suggesting that metformin differentially alters the inflammatory secretome of normal rectal tissue, when compared to rectal cancer tissue, which may support its potential utility as a radiosensitiser

It is approved for initial treatment of women with postmenopausal osteoporosis who are at high risk of fracture or have failed or been intolerant of previous osteoporosis therapy

The reasons are rarely medical: cost, early GI effects that arrive before any visible benefit, and the quiet decision that today's burden isn't worth today's payoff

The more we learn about alcohol and its effects on our body, the more informed choices we can make when drinking