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[63] first reported the existence of G protein-coupled receptor (GPCR) GLP-1R in human hepatocytes in 2010, and provided evidence to prove the direct effects of GLP-1 protein on cells

In our published research on more than a thousand patients on tirzepatide, constipation was the single most reported side effect, Dr

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Preclinical studies have reported that Exendin-4 (Ex-4) and dulaglutide display inhibitory effects on breast cancer, whereas liraglutide presents a trend of increased breast cancer incidence, with the risk ratio rising with prolonged exposure