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10.1016/j.celrep.2016.12.090 Cell Rep

This metabolite accumulates within storage vesicles, displacing endogenous norepinephrine and functioning as a false neurotransmitter ( panel 3 )

Glutathione, one of the most abundant cellular metabolites, maintains cellular environment in reduced state, protecting proteins and iron-sulfur clusters from oxidative stress and is essential for biosynthesis reactions, such as nucleotide synthesis 3

As for blood cells, only a handful of studies, with modest sample sizes and almost exclusively featuring platelets, have examined age-related mitochondrial decline, and the results have been inconclusive 18,19,20,21,22,23