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The trial to examine the efficacy of the drug for obesity started with the injection of 0.25mg of semaglutide weekly for the first 4 weeks, with the dose increased every 4 weeks to reach the maintenance dose of 2.4mg weekly by week 16 (lower maintenance doses were permitted if participants had unacceptable side effects with the 2.4mg dose)

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Cost Breakdown by Dosage (2.5mg to 15mg) Tirzepatide dosing escalates over time, but most providers charge a flat monthly rate regardless of dose