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4A), indicating the potential of these conjugates to serve as relevant clinical markers when blood samples are available, as it is in the case of acute intoxication, to monitor the elimination of the toxic NAPQI

In fact, incorporation of brachytherapy remains one of the most robust independent predictors of long-term survival, with reported local control rates exceeding 8090% in many series when combined with concurrent chemoradiation [92, 93]