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In 2024, the ESC guidelines for elevated blood pressure and hypertension classified GLP-1 RA as therapies that have shown blood pressure-lowering properties but are awaiting further supportive evidence from cardiovascular outcomes trials prior to guideline endorsement and routine use in hypertension [49]

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Acute kidney injury can happen when dehydration from vomiting or diarrhea is left untreated

Additionally, GLP-1 drugs slow down gastric emptying, helping to regulate appetite and promote weight loss in some individuals