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Available from: Wster P, Eriksson I, Vainikka L, Rosdahl I, llinger K

Diabetes 2002;51 Suppl 3(S434442

They do not replace the need for proper rehabilitation

The model was defined by five differential equations: T 1 , T 2 , and T 3 are the amount of drug in the transit compartments, C and P are the amount of drug in the central and peripheral compartments, k a and k el are the first-order absorption and elimination rate constants, k 12 and k 21 are the first-order transfer rate constants between the central and peripheral compartments, V/F is the volume of distribution, F is the bioavailability, and Cp is the drug concentration in the central compartment