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A more useful question is what kind of tissue is being lost

Lipoic acid: Women with polycystic ovary syndrome who supplemented with lipoic acid showed an improvement in insulin sensitivity and a reduction in triglycerides, while improvements in menstrual regularity were also seen with a combination of lipoic acid and inositol

Psychiatry 21 , 163171 (2009)

Upon recruitment to developing plaques, monocytes encounter many inflammatory stimuli such as damage associated molecule patterns (DAMP), oxLDL, and IFN that trigger inflammatory cascades after engagement with toll-like receptors (TLR), scavenger receptors and cytokine receptors, respectively