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While singly-housed animals may experience stress that impacts metabolism, body weight, and adiposity 65,66,67,68,69 , the singly-housed animals in this study were treated identically (to the best of the experimenters ability) to minimize and equalize stress across all animals and reduce confounding variables

A small pilot study found artificial food colorings did affect brainwave patterns in individuals with ADHD when exposed after a period of avoidance

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IP3 encourages the release of Ca from intracellular stores, increasing the cytosolic calcium concentration, while DAG activates protein kinase C (PKC)