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In addition, once-daily administration of 1 mg oral hydroxocobalamine caused the studied children's levels of homocysteine to increase and their levels of methionine to decrease, while the reverse happened when hydroxocobalamine was given intramuscularly

doi:10.1097/01.DSS.0000452629.76339.2b 40Jimenez JJ, Wikramanayake TC, Bergfeld W,

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Its reduced levels in obesity, type-two diabetes and atherosclerosis likely result from inflammation, adipose tissue hypertrophy, and oxidative stress 38