doi: 10.3389/fphar.2023.1196287 Received 29 March 2023 Accepted 02 May 2023 Published 15 May 2023 Volume 14 - 2023 Edited by Daniela Gabbia, University of Padova, Italy Reviewed by Xiao Li, Shandong Provincial Qianfoshan Hospital, China Hartmut Kuhn, Charit University Medicine Berlin, Germany Updates Copyright 2023 Lu, Hu, Chen, Li, Yuan, Tian, Cao and Qiu
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Studies suggest that viral communities can interact with gut bacteria, potentially exacerbating inflammation or influencing immune cell behavior ( 5 The interaction mechanism between gut microbiota and ferroptosis in IBD The gut microbiota regulates ferroptosis-related signaling pathways through multiple mechanisms, including (i) remodeling luminal iron availability and epithelial iron handling, (ii) rewiring host antioxidant capacity and lipid peroxidation tone via microbial metabolites, and (iii) modulating mucosal immune programs that determine the ferroptosis threshold of distinct cell types
For researchers working with NAD+ vials, understanding proper reconstitution and dosing is essential
