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Nevertheless, concerning case reports and retrospective studies have emerged in 2023 of undigested gastric contents in sedated/anaesthetised patients undergoing elective endoscopy with unprotected airways: Klein and Hobai (2023) published a case report of a patient taking semaglutide for weight loss who experienced pulmonary aspiration from undigested food content identified during routine gastroscopy, despite fasting 18hr prior to the procedure

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In what ways does the FDA ensure oral semaglutides safety for weight loss

The FDA eventually approved Wegovy (semaglutide) in 2021 for adult patients with a body mass index of: 30kg/m2 (obese) or 27 g/m2 (overweight) with at least one other weight-related comorbidity (e.g., type 2 diabetes)