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Interestingly, these effects were more pronounced in the high-dose APLA group compared to PLA, suggesting dose- and type-dependent neurotoxicity (Qian et al., 2025)

BPC-157 enhances growth hormone receptor expression, modulates VEGF and FGF signaling to promote angiogenesis and tissue repair , reduces pro-inflammatory cytokines TNF-alpha, IL-6, and IFN-gamma, and interacts with the nitric oxide system to provide endothelial protection